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Platelet Rich Plasma (PRP) and Platelet Rich Fibrin (PRF) are non-surgical treatments that use your own growth factors and blood platelets to rejuvenate skin, improving the appearance of fine lines, wrinkles, and acne scars. PRP & PRF Therapy Portland also help with hair loss and thinning.

What is PRP and PRF?

PRP (Platelet-Rich Plasma) and PRF (Platelet-Rich Fibrin) are both treatments that use a patient’s own blood components to stimulate healing and regeneration in various parts of the body.

Platelet-Rich Plasma (PRP) vs Platelet-Rich Fibrin treatment

Two-Step Centrifugation – The first spin separates the blood components, and then the platelet-rich plasma is further processed in a second spin.
It has a higher platelet concentration than whole blood but is generally lower than PRF.
Releases growth factors quickly upon application, providing healing properties.

Conditions Treated with PRP and/or PRF

acne scars


wrinkles and fine lines

skin texture

sun damage

uneven skin tone


hair loss















Which areas can PRP/PRF be injected in?

PRP and PRF can be applied topically (on top of the skin) during or after laser treatments and microneedling

Which treatment can I combine with PRP or PRF?

Using PRP and PRF in conjunction with microneedling enhances the effectiveness of the treatment. The tiny channels that the micro-needles create allow for deeper penetration of the platelet-rich components into the skin. This combination results in better outcomes and a faster recovery.
Integrating PRP & PRF with laser treatments amplifies the benefits. The laser creates micro-perforations in the skin, allowing for a deeper infusion of the platelet-rich components. This approach not only enhances skin rejuvenation but also expedites the healing process, leading to improved results and reduced downtime.

Who is a Candidate for PRP or PRF?

Individuals aiming to address hair loss, wrinkles, scars, or skin laxity

Those in overall good health

Individuals with realistic expectations about outcomes

Not pregnant or nursing

What is Recovery Like?

It is common to experience some mild discomfort or pain at the injection site. Some swelling and bruising may occur, especially in sensitive or thin skin areas. This should subside within a few days. Depending on the specific treatment area, your healthcare provider may advise against certain medications (like anti-inflammatories or blood thinners) that could interfere with the healing process.

Dr. Nancy Yen Shipley experienced in the use of ultrasound and orthobiologics in the treatment of musculoskeletal conditions. And is additionally certified in Laser treatment of medical conditions, post-surgical and post-traumatic scars, PRP, injectable neuromodulators for medical and aesthetic applications.
Ms. Kylie Farwell is a board-certified Physician Assistant and a native Idahoan. Trained in orthobiologics, PRP, ultrasound-guided interventions, laser therapy, and neuromodulators such as botox, and fillers, Kylie is passionate about helping patients overcome their post-surgical and post-traumatic scars, and present their best selves forward to the world.
Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.