Injectables, lasers, facials and regenerative care from a doctor-led team in NE Portland, with a free consultation to start.
Ortho-Rejuv Wellness and Aesthetics is a physician-led medical spa in the Providence Plaza building on NE Hoyt Street, across from Providence Portland Medical Center. Dr. Natalie Mesnier, MD, founded the practice to bring medical training to aesthetic care, so every plan starts with your skin, your health history and your goals, not a menu of add-ons. Portland patients come to us from the Hollywood District, Laurelhurst, Irvington, the Pearl and downtown for natural results that still look like them.
“After three weeks I saw major changes. My melasma is much lighter.” Emiko Kogure, patient of Dr. Mesnier · Google review
We are inside Providence Plaza on NE Hoyt Street, minutes from I-84 and the Hollywood Transit Center.
Physicians and Certified Advanced Estheticians who work together on every plan.
We are at 5050 NE Hoyt St, Suite 626, in the Providence Plaza building across from Providence Portland Medical Center in NE Portland, OR 97213.
Physician-led care, with a doctor on every treatment plan. Free consultations, with honest advice about what will and won’t help. Aerolase, fractional laser and NeoGen plasma technology in one clinic. Ageless AI preview so you can see a likely result before you commit. Cherry financing with monthly payment plans. Easy to reach from I-84 and the NE Sandy Blvd corridor.
Yes. Ortho-Rejuv is physician-led. Dr. Natalie Mesnier, MD, and Dr. Nancy Yen Shipley, MD, oversee treatment plans, and injectables are placed by our medical team.
Yes. Your first consultation is free. We review your goals and skin and give you a clear plan with pricing before you decide anything.
Yes. We offer Cherry financing, which lets many patients split treatments into monthly payments.
Wrinkle relaxers, dermal fillers, Aerolase laser treatments, DiamondGlow and Luxe facials, microneedling and PRP are among the most requested services at our Portland clinic.
Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.
Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family
Certified Advanced Esthetician
Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.
