Wrinkles and Fine Lines
Wrinkle Treatment in Portland, OR
Our team reads each line at rest and in motion, then matches it to an in-house treatment: Jeuveau or Daxxify for expression lines, dermal fillers for deep folds, and Aerolase, NeoGen or SkinPen for lines that stay.
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See Your PotentialResults
Wrinkle Treatment Before and After
Results with treatments on our wrinkle menu: Jeuveau, NeoGen and Aerolase. Individual results vary with skin type, wrinkle depth and number of sessions.
Know Your Lines
Two Kinds of Wrinkles, Two Approaches
Wrinkles form as skin loses the collagen and elastin that keep it firm and smooth. Age, sun exposure, smoking, genetics and repeated expressions all speed up that loss. Where a line comes from decides what will soften it.
Movement
Dynamic Lines
These appear when you frown, raise your brows or squint, then fade when your face relaxes: the 11s, forehead lines and crow's feet.
Responds to: wrinkle relaxers that calm the muscle beneath the crease.
Collagen loss
Static Lines
These stay visible at rest because the skin itself has thinned: etched forehead lines, lines around the mouth, crepey under-eye skin and neck lines.
Responds to: collagen-building treatments such as laser resurfacing, NeoGen and microneedling.
When to Book an Assessment
Many people have both, and a frown line can become etched over the years. Book an assessment when lines stay after your face relaxes, when makeup settles into them, or when skincare no longer helps.
Our Wrinkle Menu
Matching the Treatment to the Line
Every option below is offered in our own clinic, so one plan can combine them based on wrinkle type, depth and the downtime you can allow.
| Treatment | Treats | How it works | Typical plan |
|---|---|---|---|
| Jeuveau and Daxxify | Frown lines, forehead lines, crow's feet | Injections relax the muscles that crease the skin. | One short visit, with touch-ups every few months |
| Dermal Fillers | Deep folds and etched lines around the mouth | Filler restores support beneath a crease so it looks softer at rest. | Usually one visit, with touch-ups over time |
| Aerolase Age Reverse | Fine lines, uneven texture and pigment | Dual laser: deep dermal stimulation plus surface resurfacing. | A series of 3 to 5 sessions, minimal downtime |
| Laser Skin Resurfacing | Deeper wrinkles from collagen loss | Removes damaged surface layers; fractional mode shortens recovery. | A few days of redness or peeling with deeper settings |
| NeoGen Plasma Resurfacing | Crow's feet, crepey skin, the delicate eye area | Nitrogen plasma remodels collagen under an intact top layer. | Results keep developing for months after treatment |
| SkinPen Microneedling with PRP or PRF | Fine lines, neck wrinkles, rough texture | Micro-channels stimulate collagen; your own plasma can be added. | About 30 to 60 minutes per session, planned as a series |
| PRF EZ-Gel | Folds and hollows from lost volume | A gel made from your own plasma restores lost volume. | Discussed at your consultation |
What to Expect
Your Wrinkle Plan, Step by Step
Assessment
Your provider studies your face at rest and in motion, reviews your health history and asks about your goals.
Your Plan
One treatment or a pairing, such as Jeuveau for the 11s plus a NeoGen series, with an exact quote first.
Treatment Day
Numbing cream is applied when needed. Injections take minutes; energy and microneedling sessions usually under an hour.
Results and Review
Relaxers settle in over about two weeks and collagen builds for months. We review progress at follow-up visits.
Our Practice
Founded by Dr. Natalie Mesnier, MD
Dr. Natalie Mesnier, MD · Founder
Dr. Natalie Mesnier founded our medical spa. She has a background in aesthetic medicine, holds certifications in advanced aesthetic procedures including PRP and neuromodulator applications, and is skilled in anti-aging laser therapies, injectables and fillers.
Wrinkle treatments are provided by our team of certified advanced estheticians and medical staff. We do not push a single device: your lines are matched to the treatment that addresses their cause.
Practice Reviews
What Patients Say About Our Practice
Venus is highly skilled and dedicated. She checked on me daily while I was recovering, and I knew I was in good hands.Robyn Washburn · NeoGen Plasma Resurfacing
Cassidy and Dr Mesnier were so knowledgeable about possible treatments that would work best for me.Tonya Flaming · Consultation
5.0 average rating across 28 Google reviews
Between Visits
Protecting Results With Daily Care
Sun exposure is one of the main drivers of wrinkles, so daily sunscreen and gentle skincare are part of the aftercare every patient receives.
Your provider can also build a routine from our own Ortho-Rejuv skincare line, such as the CE+ Ultimate Age Defying Serum, AM Eye Cream and Age Defying Restorative Moisturizer, chosen for your skin type.
- Light Stim LED as an add-on to support collagen between sessions
- Medical-grade chemical peel to refine texture and tone
- T-Shape 2 Face and Décolleté for firmness along the face, neck and chest
Cost and Location
Planning Your Treatment
Cost of Wrinkle Treatment in Portland, OR
Cost depends on the treatment or combination, the size of the area and the number of sessions. Wrinkle relaxers are priced per unit; laser, NeoGen and microneedling are usually planned as a series.
You receive an exact quote at your complimentary consultation, and monthly payment plans are available through Cherry.
Visiting Our Clinic
We are in the Providence Plaza building at 5050 NE Hoyt St #626, Portland, OR 97213, across the street from Providence Hospital rather than inside the hospital building.
- Mon to Thu
- 8:00am to 5:00pm
- Friday
- 10:00am to 4:00pm
- Saturday
- 9:00am to 2:00pm
- Sunday
- Closed
FAQ
Wrinkle Treatment Questions
Which wrinkle treatment is right for me?
It depends on the type of line. Expression lines usually respond to Jeuveau or Daxxify, while lines that stay at rest need a collagen-building treatment such as Aerolase, laser resurfacing, NeoGen or SkinPen, and many patients do well with a combination.
How long do wrinkle relaxers last?
Jeuveau and Daxxify results typically last a few months before a touch-up. Daxxify uses a peptide-based formula, and your provider can explain how its timing compares with Jeuveau.
How many sessions will I need?
Wrinkle relaxers take one short appointment with periodic touch-ups. Aerolase Age Reverse is typically a series of 3 to 5 sessions, and NeoGen or microneedling series are sized to the depth of your lines.
Is there downtime after wrinkle treatment?
Most wrinkle treatments have little to no downtime. Deeper laser or NeoGen treatments may bring a few days of redness or peeling, and your provider explains the expected recovery before you book.
Can you treat wrinkles on darker skin tones?
Yes. Our team works with all skin types and tones, and your provider chooses the treatment and its settings with your skin type in mind.
Can I combine wrinkle relaxers with laser or NeoGen?
Yes, and many plans do. A relaxer softens the movement that creases the skin, while a laser, NeoGen or microneedling series rebuilds collagen in lines that have already set.
Complimentary Consultation
Start With a Wrinkle Assessment
Leave knowing which lines are dynamic, which are static and what will soften each one.
5050 NE Hoyt St #626, Portland, OR 97213
