NAD+ Shots in Portland, OR
A quick NAD+ injection given after a health review by our medical team, on its own or as a booster added to your IV therapy appointment.
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What a NAD+ Shot Is
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell. Cells rely on it to turn food into usable energy, to repair DNA and to support healthy brain function. Levels fall naturally as we age, which is why many patients add NAD+ to a longevity-focused routine.
A NAD+ shot delivers it by injection into the upper arm in a short visit. It is the quick alternative to a full infusion: you can book it as a stand-alone appointment, or add it as a booster when you come in for IV therapy.

Shot, IV or Capsule: How They Compare
We offer two ways to receive NAD+: a shot and NAD+ IV therapy. Many patients also ask how both compare with the capsules sold online, so here is the plain version.
| NAD+ Shot | NAD+ IV Therapy | Oral Capsule | |
|---|---|---|---|
| How it is given | Injection into the upper arm | Infusion into a vein over a longer session | Swallowed daily at home |
| Time in our office | A short visit; the injection takes moments | A longer infusion appointment | None |
| What it contains | NAD+ itself | NAD+ itself, delivered into the bloodstream | Usually precursors the body must convert after digestion |
| Medical oversight | Health review by our team first | Health review by our team first | Self-directed |
| Pairs well with | An IV therapy visit, as a booster | Patients who prefer an infusion | Ask us before combining with a shot |
Not sure which suits you? We help you choose at your health review, including whether a shot paired with IV therapy fits your goals.
Who Chooses a NAD+ Shot
NAD+ shots may suit healthy adults who want convenient wellness support. These are the patients we see most often.
Longevity-Minded Adults
Healthy adults focused on aging well who want to replenish a coenzyme that declines with age.
People Who Feel Run Down
Patients interested in supporting cellular energy alongside sleep, nutrition and exercise.
Short on Time
Patients who cannot fit a full infusion into their week and prefer a visit measured in minutes.
IV Therapy Patients
People already on our IV therapy menu who want to add NAD+ as a booster at the same visit.
If you are pregnant or breastfeeding, or you manage a medical condition, we may ask you to check with your physician first.
Your Visit, Step by Step
Health Review
We go over your medical history, medications, supplements, allergies and wellness goals to confirm a NAD+ shot is appropriate.
Preparation
The injection site on your upper arm is cleaned, and we answer any last questions.
Injection
The NAD+ shot is given with a small needle. The injection itself takes only moments.
Back to Your Day
There is no downtime. Mild soreness, redness or a small bruise at the site can last a day or so.
Before Your Shot
No special preparation is needed. Eat normally, stay hydrated and wear a top that leaves your upper arm easy to reach.
After Your Shot
Keep drinking water and avoid rubbing the injection site. Tell our team about any reaction that feels unusual.
What NAD+ Shots Can and Cannot Do
NAD+ injections get a lot of attention, and research on them is still developing. We would rather you book with clear expectations, so this is where we stand.
A NAD+ Shot Can
- Replenish a coenzyme your cells use to produce energy
- Fit a longevity routine in a visit of a few minutes
- Add to an IV therapy appointment as a booster
- Be paired with our team's review of your health and goals
A NAD+ Shot Cannot
- Replace medical care for a diagnosed condition
- Stand in for sleep, nutrition and exercise
- Melt belly fat or act as a weight-loss treatment
- Promise the same result for everyone; individual results vary

Founded by Dr. Natalie Mesnier, MD
MD, Founder
Dr. Mesnier founded Ortho-Rejuv Wellness and Aesthetics. She holds certifications in advanced aesthetic procedures, including PRP and neuromodulator applications.
NAD+ shots and our other wellness services are provided by our team of Certified Advanced Estheticians and medical staff. Every NAD+ shot starts with a health review, and our team helps you choose a shot, an infusion or a combination with IV therapy that matches your goals.
NAD+ Shot Pricing and Financing
NAD+ shots are offered as single visits or as a booster add-on to IV therapy, and members of our wellness program receive member pricing. Current rates are listed on our medspa pricing page.
Monthly payment plans are available through our financing partner, Cherry.
NAD+ Shot Questions, Answered
Have a question that is not here? Bring it to your free consultation and our team will walk through it with you.
How is a NAD+ shot different from NAD+ pills?
Most capsules sold as NAD+ support contain precursors that your body has to convert after digestion. A shot places NAD+ itself into the tissue, so it does not depend on the gut. Capsules are taken daily at home, while a shot is a short in-office visit given after a health review.
Does NAD+ reduce belly fat?
We do not offer NAD+ shots as a weight-loss or fat-reduction treatment. NAD+ plays a role in how cells produce energy, but it is not a substitute for nutrition, exercise or a medical weight plan. If body contouring is your goal, ask us about T-Shape 2 at your consultation.
What should I avoid after a NAD+ injection?
There is no downtime, so you can go back to your day right away. Avoid rubbing or pressing on the injection site, keep drinking water, and expect that the spot may feel sore or look a little red for a day or so. Let our team know about any reaction that feels unusual.
How can I tell if NAD+ is working?
There is no single sign, and individual results vary. Many patients keep simple notes on energy, focus and sleep over several weeks of shots, then review them with our team to decide whether to continue.
Can I add a NAD+ shot to my IV therapy appointment?
Yes. A NAD+ shot can be a stand-alone visit or a booster added to an IV therapy appointment. Patients who prefer a longer infusion can choose NAD+ IV therapy instead.
How long does a NAD+ shot visit take?
The injection itself takes only moments, so a NAD+ shot fits into a short visit. Your first visit also includes a health review with our team before the shot is given.
Can I get a NAD+ shot if I am pregnant or have a medical condition?
If you are pregnant or breastfeeding, or you manage a medical condition, we may ask you to check with your physician first. Our team reviews your history, medications, supplements and allergies before any shot is given.
Book Your NAD+ Shot in Portland
Start with a free consultation or book your shot directly. We can add it to your next IV therapy visit.





