Hand Rejuvenation for Aging Hands in Portland, OR
We treat volume loss, sun spots and crepey skin on the backs of the hands as three separate concerns, each with its own treatment, in one plan.
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Real Results on Real Hands
One patient, two hands. Only the hand on the right was treated, so the difference is easy to see: its skin looks smoother, with softer fine lines across the knuckles and the back of the hand.
- Treatment
- Diamond Glow exfoliation, extraction and infusion
- Serum
- TNS Advanced+ Serum for fine lines and wrinkles
- Best for
- Dull, finely lined skin, often alongside other treatments
Why Hands Show Age Early
The backs of the hands have thin skin and very little fat to begin with. They also get years of sun and rarely get sunscreen, so they can look older than the face.
Have a Spot Checked First
A spot that grows, bleeds, itches or looks different from the others needs a medical check before any cosmetic treatment. We tell you if we see one.
Volume Loss
Collagen and fat decrease with age, so veins and tendons become more visible and knuckles look bonier.
Sun Spots
Years of sun exposure leave brown spots and uneven tone across the back of the hand.
Crepey Texture
Loss of elasticity leaves thin, finely wrinkled skin that creases when you make a fist.
One Treatment for Each Sign
Aging hands rarely show only one sign, so we treat by concern and combine what your hands need.
- Concern 01
Volume
Visible veins and tendons, hollows between the bones.
Fillers and biostimulators - Concern 02
Spots
Sun spots, freckling and uneven pigment.
Aerolase laser - Concern 03
Texture
Thin, finely wrinkled skin that has lost its spring.
NeoGen plasma resurfacing
To Refine the Result
Medical-grade chemical peels, SkinPen microneedling and Diamond Glow further improve tone and texture between or after your main treatments.

Restoring Volume With Fillers and Biostimulators
Dermal filler placed in the back of the hand adds a soft layer over veins and tendons, so they show less.
Collagen-stimulating biostimulators work differently: they prompt your own skin to rebuild support over the following weeks, for a gradual, longer-lasting result.
- Softens the look of veins and tendons
- Planned to look refreshed, not overdone
- Pairs with laser and plasma in the same plan
Aerolase and NeoGen in Our Treatment Room
Two devices treat the surface of the skin, both run by our own team in Portland.
Aerolase Laser
Targets sun spots and uneven pigment on the backs of the hands for a clearer, more even tone.
NeoGen Plasma
Uses nitrogen plasma energy to stimulate collagen and renew thin, crepey skin from beneath the surface. Results continue to develop over the following weeks.
"Recently I received a Neogen Plasma Resurfacing treatment at Ortho-Rejuv, and even though it's only my second week, I am really impressed with the results so far."
Robyn W., Google review
Your Hand Rejuvenation Plan, Step by Step
Most plans run over a few visits, in an order that lets each treatment build on the last.
Consultation
We look at volume, pigment and texture on both hands and talk through your goals.
Free consultationYour Plan
We recommend which treatments to combine, in what order, and quote the price.
Before any treatmentTreatment Sessions
Sessions take place in our Portland office. A microneedling session, for example, takes about 30 to 60 minutes.
Often a few visitsMaintenance
Daily sunscreen on your hands and occasional maintenance sessions keep the result.
Ongoing
Founded by Dr. Natalie Mesnier, MD
Hand rejuvenation is provided by our team of certified advanced estheticians and medical staff, who work with every skin type and tone.

Dr. Natalie Mesnier
MD, FounderDr. Mesnier founded our medical spa and brings a background in aesthetic medicine, laser therapies, injectables and fillers.
Cost and Financing
The cost of hand rejuvenation depends on the treatments in your plan and how many sessions you need. We quote your price at the consultation, so you know it before you begin.
Pay Over Time With Cherry
Many patients spread the cost of a treatment series with monthly payments through our financing partner, Cherry.
See Our Current Menu
Prices for each treatment on our menu are listed on our medspa pricing page.
Hand Rejuvenation Questions
What is the best treatment for hand rejuvenation?
There is no single best treatment, because most aging hands show more than one sign. Fillers or biostimulators restore volume, the Aerolase laser targets sun spots, and NeoGen plasma, microneedling and peels improve crepey texture. We often combine them.
How much does hand rejuvenation cost in Portland, OR?
It depends on the treatments in your plan and the number of sessions. We quote your price at a free consultation, our current menu is on the medspa pricing page, and monthly payments are available through Cherry.
What causes veins and tendons to show on my hands?
The backs of the hands have thin skin and little fat. As collagen and volume decrease with age, veins and tendons become easier to see. Filler in the back of the hand softens their look.
Can crepey skin on the hands improve?
Yes. NeoGen plasma, SkinPen microneedling and medical-grade chemical peels all stimulate collagen, which helps thin, crepey skin look smoother over time.
How many sessions will I need?
It depends on how many signs you are treating and which treatments your plan uses. We map out the number and order of sessions at your consultation.
How do I protect my results?
Wear sunscreen on the backs of your hands every day, since sun exposure causes new spots. Maintenance sessions help keep volume and texture where you want them.
Book Your Free Hand Consultation
Show us your hands, and leave with a plan for volume, spots and texture.
5050 NE Hoyt St #626, Portland, OR 97213 · Providence Plaza, across the street from Providence Hospital





