A doctor-led med spa about 20 minutes across the I-5 or I-205 bridge, with a free consultation to start.
Many of our patients live in Vancouver, WA, Camas and Battle Ground and cross the river to see us. Ortho-Rejuv Wellness and Aesthetics is a physician-led medical spa in NE Portland, a short drive down I-205 or I-5 to NE Hoyt Street. Dr. Natalie Mesnier, MD, and our team plan each treatment around your skin and your schedule, and we keep visits efficient, so the drive is worth it and you are back across the bridge without losing your day.

“My acne has drastically improved, and my dark melasma and uneven tone have also noticeably faded.” Edna Galope, patient of Dr. Mesnier · Google review
Take I-205 south to I-84 west, or I-5 south to I-84 east, and exit toward NE Sandy Blvd. We are inside Providence Plaza on NE Hoyt Street.
Physicians and Certified Advanced Estheticians who plan every treatment together.




Our clinic is in NE Portland, OR, at 5050 NE Hoyt St, Suite 626. Most Vancouver patients reach us in about 20 minutes by I-205 or I-5.
Physician-led medical spa, with doctors on every treatment plan. About 20 minutes from central Vancouver via I-205 or I-5. Free consultations, so you know the plan before you commit. Microneedling, Aerolase laser, injectables and PRP under one roof. Ageless AI preview of your likely result. Cherry financing with monthly payment plans.
Many patients think so. You get a physician-led team, a free consultation and treatments like Aerolase laser, NeoGen plasma and PRP in one clinic, and most visits take under an hour.
Often, yes. Your provider can plan treatments that pair well, such as a facial with a wrinkle relaxer, so you make fewer trips.
Bring a list of any medications and skin products you use and photos of results you like. We take care of the rest at your free consultation.
Use the Book Appointment button on this page or call (503) 446-6360. Your first consultation is free.

Venus is a Certified Advanced Esthetician, Certified Phlebotomy Technician, and pre-nursing student with a passion for medical aesthetics and patient-centered care. She is dedicated to helping clients achieve healthy, radiant skin through result-driven, customized treatments tailored to their unique needs. As a patient advocate at heart, Venus loves working with all skin types and creating long-term skincare plans that focus on both visible results and overall skin health.
Her favorite treatments include Aerolase, NeoGen, and microneedling, innovative treatment options that deliver real, transformative outcomes. Outside of the treatment room, Venus enjoys creating social media content, exploring new food spots, and spending time with friends and family

Certified Advanced Esthetician




Dr. Natalie Mesnier, the driving force behind Ortho-Rejuv Wellness and Aesthetics, stands at the forefront of aesthetic innovation. With a rich background in the aesthetic realm, she is notably skilled in anti-aging laser therapies, skin revitalization, and the meticulous use of injectables and fillers. Alongside her certifications in advanced aesthetic procedures, including PRP and neuromodulator applications, Dr. Mesnier’s mission is singular: to empower patients to experience and radiate their utmost beauty and confidence.